model.it: building three dimensional DNA models from sequence data

Citation
K. Vlahovicek et S. Pongor, model.it: building three dimensional DNA models from sequence data, BIOINFORMAT, 16(11), 2000, pp. 1044-1045
Citations number
16
Categorie Soggetti
Multidisciplinary
Journal title
BIOINFORMATICS
ISSN journal
13674803 → ACNP
Volume
16
Issue
11
Year of publication
2000
Pages
1044 - 1045
Database
ISI
SICI code
1367-4803(200011)16:11<1044:MBTDDM>2.0.ZU;2-M
Abstract
A WWW sewer is described for creating 3D models of canonical or bent DNA st arting from sequence data. Predicted DNA trajectory is first computed based on a choice of di- and tri-nucleotide models (M.G.Munteanu et al., Trends Biochem. Sci. 23, 341-347, 1998); an atomic model is then constructed and o ptionally energy-minimized with constrained molecular dynamics. The data ar e presented as a standard PDB file, directly viewable on the user's PC usin g any molecule manipulation program.