A general method for the formation of zinc enolate equivalents from iodoacetates by diisopropylzinc-iodine exchange reaction: Preparation of beta-hydroxy esters

Authors
Sato, I Takizawa, Y Soai, K
Citation
I. Sato et al., A general method for the formation of zinc enolate equivalents from iodoacetates by diisopropylzinc-iodine exchange reaction: Preparation of beta-hydroxy esters, B CHEM S J, 73(12), 2000, pp. 2825-2826
Citations number
18
Categorie Soggetti
Chemistry
Journal title
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
ISSN journal
00092673 → ACNP
Volume
73
Issue
12
Year of publication
2000
Pages
2825 - 2826
Database
ISI
SICI code
0009-2673(200012)73:12<2825:AGMFTF>2.0.ZU;2-W
Abstract
Diisopropylzine is found to be a highly efficient reagent for the formation of zinc enolate equivalents from various iodoacetates via iodine-zinc exch ange reaction at room temperature, affording beta -hydroxy esters in high y ields by the reaction with aldehydes and ketones.