The human vomeronasal duct (VND) is described as a tubular or pouch-like mu
cosal invagination of the anterior nasal septum. This study investigated sh
ape, size and orientation of the VND using magnetic resonance imaging (MRI)
. Fifteen subjects participated (eight women, seven men; mean age 39 years,
age range 18-66 years); they had been pre-selected with regard to the pres
ence of a VND opening of mm. MRI was performed before and after application
of diluted gadolinium-diethylene-triamino-penta-acetic actetate (Gd-DTPA)
into the left or rig ht VND. A tubular structure was found in 12 subjects w
ith a median length of 7 mm (range 3-22 mm; one VND with a length 47 mm). I
n three subjects a nearly circular, pouch-like structure was observed. Seve
n of the tubular VNDs were slightly bent upwards, the other five VNDs ran p
arallel to the floor of the nasal cavity. There was no significant gender-r
elated difference in the length of VNDs. These data indicate considerable v
ariability of shape, size and orientation of the human VND.