Mp. Mintchev et al., Misinterpretation of human electrogastrograms related to inappropriate data conditioning and acquisition using digital computers, DIG DIS SCI, 45(11), 2000, pp. 2137-2144
Despite the fact that digital techniques for data acquisition and processin
g were widely used in electrogastrographic (EGG) research during the last d
ecade, inappropriate signal conditioning and digitization are still potenti
al pitfalls threatening the reliability of the experiments. The aim of this
paper was to review: (1) the importance of the antialiasing low-pass filte
ring for reducing recording artifacts and interferences, (2) the advantages
brought by the proper choice of filter cutoff frequency and the slope for
the decrement of the minimal required sampling frequency, (3) the impact of
incorrectly selected sampling frequency on data interpretations, with part
icular attention to the percent distribution ranges, and (4) the "leakage e
ffect" related to the finite number of samples processed simultaneously in
frequency domain representation of the recordings. A model of electrogastro
graphic (EGG) recording was mixed with a model of electrocardiographic (ECG
) artifact. The resulting finite-duration signal was low-pass filtered and
then digitized with a sampling frequency of 1 fit. The cutoff frequency of
the first-order low-pass filter was altered from 0.5 to 0.1 Hz. Amplitude f
requency spectra of the digitized recordings were investigated. An example
with a real human electrogastrogram in which an ECG artifact was present co
nfirmed the simulation results. When a first-order anti-aliasing filter is
utilized at least a fivefold difference between the filter cutoff frequency
and the sampling frequency is recommended for compliance with the Nyquist
theorem of digitization. Leakage effects associated with the finite-time du
ration of the recordings and the use of the discrete Fourier transform shou
ld be considered when frequency domain analysis is performed. Misinterpreta
tion of the "bradygastric" and "tachygastric" ranges in the percent distrib
ution of EGG frequency components is possible if inappropriate signal condi
tioning and digitization are employed.