Cirrhosis with non alcoholic steatohepatitis: role of tamoxifen

We report a case of non-alcoholic steatohepatitis with cirrhosis in a woman receiving tamoxifen as adjuvant treatment For breast cancer. Despite the p resence of other risk factors for non-alcoholic steatohepatitis (such as di abetes, obesity and hyperlipidemia), the patient developed non-alcoholic st eatohepatitis and cirrhosis only after tamoxifen was started. We suggest th at patients receiving tamoxifen, especially patients with predisposing meta bolic disorders, should be evaluated For non-alcoholic steatohepatitis, bec ause progression to cirrhosis may occur.