Sm. Althuisius et al., Loop electrosurgical excision procedure of the cervix and time of deliveryin subsequent pregnancy, INT J GYN O, 72(1), 2001, pp. 31-34
Objective: To study the effect of the loop electrosurgical excision procedu
re (LEEP) on gestational age at delivery in the subsequent pregnancy. Metho
d: Identification of women with LEEP. Chart analysis and inquiry into gesta
tional age at the subsequent delivery. Exclusion of first trimester abortio
ns, multiple gestations, cold knife conizations and women over 40 years dur
ing LEEP. For comparison, 40 weeks was used as the mean date of delivery in
a normal population. Wilcoxon signed rank test was used and P < 0.05 was c
onsidered significant. Result: Fifty-six women delivered after LEEP. Seven
delivered preterm of whom three were induced and one had a history of prete
rm delivery. Deliveries prior to 32 weeks of gestation did not occur. Mean
gestational age at delivery was 39 2/7 weeks (95%CI: 38 5/7-39 6/7) which i
s significantly earlier (P = 0.03) than the hypothetical 40 weeks. Conclusi
on: After LEEP, deliveries prior to 32 weeks did not occur. Gestational age
at delivery was only 5 days earlier than expected. LEEP cannot be consider
ed a risk for early preterm delivery. (C) 2001 International Federation of
Gynecology and Obstetrics. All rights reserved.