Use of penicillin MICs to predict in vitro activity of other beta-lactam antimicrobial agents against Streptococcus pneumoniae

Authors
Brueggemann, AB Pfaller, MA Doern, GV
Citation
Ab. Brueggemann et al., Use of penicillin MICs to predict in vitro activity of other beta-lactam antimicrobial agents against Streptococcus pneumoniae, J CLIN MICR, 39(1), 2001, pp. 367-369
Citations number
10
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
39
Issue
1
Year of publication
2001
Pages
367 - 369
Database
ISI
SICI code
0095-1137(200101)39:1<367:UOPMTP>2.0.ZU;2-2
Abstract
Linear regression analysis was used to compare penicillin MICs determined w ith 3,129 recent clinical isolates of Streptococcus pneumoniae to MICs obta ined with nine other beta-lactam antimicrobial agents. A strong correlation between penicillin MICs and those obtained with other beta-lactams was dem onstrated. It may be possible to test penicillin and use MICs obtained with penicillin to predict MICs of other beta-lactam antimicrobials for Strepto coccus pneumoniae.