K. Minatoya et al., Long-term pathological changes of expanded polytetrafluoroethylene (ePTFE)suture in the human heart, J HEART V D, 10(1), 2001, pp. 139-142
Expanded PTFE (ePTFE) sutures have been used widely as a mitral chordal sub
stitute. We present a structural analysis of ePTFE sutures implanted as art
ificial chordae for 7.5 years and 8.6 years in patients with mitral regurgi
tation. No calcification was found either macroscopically or microscopicall
y, and the ePTFE suture retained its normal flexibility. The suture was tot
ally encapsulated with host tissues composed of dense fibrous tissue covere
d with endothelial cells.