Mc. Geloso et al., CALRETININ-CONTAINING NEURONS IN TRIMETHYLTIN-INDUCED NEURODEGENERATION IN THE RAT HIPPOCAMPUS - AN IMMUNOCYTOCHEMICAL STUDY, Experimental neurology, 146(1), 1997, pp. 67-73
The present study uses immunocytochemistry to investigate the behavior
of the calretinin (CR)-containing neuronal subpopulation (interneuron
s) of the rat hippocampus in neurodegenerative processes induced by th
e neurotoxicant trimethyltin. Cell counts of CR-immunolabeled interneu
rons indicated that these cells are spared by the neurotoxicant-induce
d degeneration, characterized by a generalized neuronal loss, as shown
by quantitative analysis after cresyl violet staining. (C) 1997 Acade
mic Press.