CALRETININ-CONTAINING NEURONS IN TRIMETHYLTIN-INDUCED NEURODEGENERATION IN THE RAT HIPPOCAMPUS - AN IMMUNOCYTOCHEMICAL STUDY

Citation
Mc. Geloso et al., CALRETININ-CONTAINING NEURONS IN TRIMETHYLTIN-INDUCED NEURODEGENERATION IN THE RAT HIPPOCAMPUS - AN IMMUNOCYTOCHEMICAL STUDY, Experimental neurology, 146(1), 1997, pp. 67-73
Citations number
35
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
00144886
Volume
146
Issue
1
Year of publication
1997
Pages
67 - 73
Database
ISI
SICI code
0014-4886(1997)146:1<67:CNITN>2.0.ZU;2-X
Abstract
The present study uses immunocytochemistry to investigate the behavior of the calretinin (CR)-containing neuronal subpopulation (interneuron s) of the rat hippocampus in neurodegenerative processes induced by th e neurotoxicant trimethyltin. Cell counts of CR-immunolabeled interneu rons indicated that these cells are spared by the neurotoxicant-induce d degeneration, characterized by a generalized neuronal loss, as shown by quantitative analysis after cresyl violet staining. (C) 1997 Acade mic Press.