AGE-DEPENDENT EXPRESSION OF THE APAMIN-SENSITIVE CALCIUM-ACTIVATED K-MUSCLE( CHANNEL IN FAST AND SLOW RAT SKELETAL)

Authors
VERGARA C RAMIREZ BU
Citation
C. Vergara et Bu. Ramirez, AGE-DEPENDENT EXPRESSION OF THE APAMIN-SENSITIVE CALCIUM-ACTIVATED K-MUSCLE( CHANNEL IN FAST AND SLOW RAT SKELETAL), Experimental neurology, 146(1), 1997, pp. 282-285
Citations number
24
Categorie Soggetti
Neurosciences
Journal title
Experimental neurology → ACNP
ISSN journal
00144886
Volume
146
Issue
1
Year of publication
1997
Pages
282 - 285
Database
ISI
SICI code
0014-4886(1997)146:1<282:AEOTAC>2.0.ZU;2-#
Abstract
An altered expression of the apamin-sensitive K+ channel from skeletal muscle is apparently implicated in human myotonic dystrophy (MD). We found, in rats, that the expression of this channel depends on age and the type of muscle. This result may be one of the bases of the differ ent susceptibilies of fast and slow muscles to drug-induced myotonia. (C) 1997 Academic Press.