Rm. Kline et al., Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children, J PEDIAT, 138(1), 2001, pp. 125-128
In a randomized, double-blind controlled trial, 42 children with irritable
bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil
capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil
had reduced severity of pain associated with IBS. Peppermint oil may be use
d as a therapeutic agent during the symptomatic phase of IBS.