NMR study of hetero-association accompanying self-association of 2-hydroxyl-4-methyl-pyridine and 2-pyrrolidone in acetonitrile

Citation
Wc. Luo et al., NMR study of hetero-association accompanying self-association of 2-hydroxyl-4-methyl-pyridine and 2-pyrrolidone in acetonitrile, J CHIN CHEM, 47(6), 2000, pp. 1177-1183
Citations number
16
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
ISSN journal
00094536 → ACNP
Volume
47
Issue
6
Year of publication
2000
Pages
1177 - 1183
Database
ISI
SICI code
0009-4536(200012)47:6<1177:NSOHAS>2.0.ZU;2-M
Abstract
This work investigated not only the equilibrium of self-association of 2-py rrolidone (A) and that of 2-hydroxyl-4-methyl-pyridine (B), but also the he tero-association between A and B in [H-2(3)]acetonitrile through hydrogen b onding using high-resolution nuclear magnetic resonance spectroscopy. Dilut ion shift data for the protons of the NW group of A and OH group of B were measured over a wide range of temperatures and concentrations. In addition, the monomer shifts, dimer shifts and dimerization constants of self-associ ation and hetero-association were evaluated using a graphic method operatin g on the dilution chemical shift data. The enthalpy and entropy of dimeriza tion of self-association and hetero-association were also obtained from the van't Hoff plot.