Flavonoid aglycones and indole alkaloids from the roots of Acacia confusa

From the methanolic extract of the roots of Acacia confusa Merr. (Leguminos ae), (-)-2,3-cis-3,4-cis-4'-methoxy-3,3',4,7,8-pentahy droxyflavan (1), (-) -2,3-cis-3,4-cis-3,3',4,4',7,8-hexahydroxyflavan (2), (-)-2,3- trans-3',4', 7,8-tetrahydroxydihydroflavonol (3), (+)-catechin (4), (-)-epicatechin (5), 3 ',4',7, 8-tetrahydroxyflavonol (6) together with N-methyltryptamine (7) and N,N-dimethyltryptamine (8) were isolated, and their structures were est ablished by analysis of their spectroscopic data. Among them, compound 1 wa s a new flavonoid. Additionally, the results of chromatographic bioassay on lettuce seeds indicated that compounds 7 and 8 exhibited significant phyto toxicity at a concentration lower than 14 mM.