Radiation therapy for extensive actinic keratosis

Actinic keratosis in the most common premalignant keratotic tumour of sun-e xposed skin. A 66-year-old man developed a large actinic keratosis on his s calp, which did not respond to conventional treatment. Fractionated radioth erapy with a cumulative dose of 28 Gy resulted in complete remission withou t relapse during a 14-month follow-up. In older subjects in whom convention al treatment fails, low-dose fractionated radiation therapy is an effective alternative method.