Objective: To describe the role of OtoScan laser-assisted myringotomy (OtoL
AM) for indications other than chronic otitis media or recurrent acute otit
is media. Study Design: Cross-sectional review. Methods: Twenty-seven offic
e-based OtoLAM procedures were performed in 21 patients for "atypical" reas
ons. The indications included middle ear dysfunction with necessary air tra
vel (n = 10) or hyperbaric oxygen treatment (n = 6), mastoiditis with posta
uricular cellulitis (n = 2), canal exostosis prohibiting tympanostomy (n =
1), acute otitis media accompanied by seizures (n = 1), and chronic middle
ear effusion in a patient with hemophilia (n = 1). Results: In each of the
20 cases available for follow-up, middle ear disease resolved with closure
of the laser-assisted myringotomy, At a later date, two patients (10%) unde
rwent another OtoLAM in the opposite ear and four patients (20%) required r
epeat OtoLAM in the same or both ears. Three patients (15%) ultimately unde
rwent myringotomy tube placement because of recurrent middle ear dysfunctio
n. Conclusions: Although this report contains preliminary data, the data su
ggest that OtoLAM may provide an additional option in the care of certain p
atients who have previously been treated with myringotomy tubes.