Diet and cardiovascular risk in Spain (DRECE II study). Description of theevolution of cardiovascular profile

BACKGROUND: To describe the evolution of cardiovascular profile in a sample of the Spanish general population. PATIENTS AND METHOD: Study cohort of 1,800 subjects from the Diet and Cardi ovascular Risk in Spain study (DRECE I) with and without cardiovascular ris k according to Spanish Society of Arteriosclerosis guidelines (CRSSA) follo wed during five years. RESULTS: Mean follow up was 4.8 years. High blood pressure (> 140/90 mmHg), total cholesterol > 200 mg/dl, triglycerides > 150 mg/dl and HDLc < 35 mg/ dl were present in a 55,6, 85,8, 42.9 and 13.4%, respectivelly of the indiv iduals with CRSSA. A 31% of those without CRSSA developed hypercholesterole mia and a 11.5% hypertension. Stroke, transient isquemic attack, angor and acute miocardial infarction appeared in 4, 3, 12 and 12 cases in the group with CRSSA and 5, 0, 1 and 1 in the groups without CRSSA. The incidence of acute myocardial infaction was 3.3 and 1.2/1,000 persons-year in the groups with/without CRSSA, respectivelly, Triglycerides were associated to the pr esence of acute myocardial infaction (OR = 10.08; IC95%; 2.1-46.4). CONCLUSIONS: There is a worsening of the cardiovascular risk profile in the cohort. Individuals with CRSSA have a worse cardiovascular risk profile th an those without CRSSA. The cardiovascular risk factors tend to be grouped in the same subjects.