A CONVENIENT SYNTHESIS OF 3-IODOHOMOALLYLIC ALCOHOLS AND THE FURTHER TRANSFORMATION TO ALPHA,BETA-UNSATURATED GAMMA-LACTONES

Authors
ZHANG CM LU XY
Citation
Cm. Zhang et Xy. Lu, A CONVENIENT SYNTHESIS OF 3-IODOHOMOALLYLIC ALCOHOLS AND THE FURTHER TRANSFORMATION TO ALPHA,BETA-UNSATURATED GAMMA-LACTONES, Tetrahedron letters, 38(27), 1997, pp. 4831-4834
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
27
Year of publication
1997
Pages
4831 - 4834
Database
ISI
SICI code
0040-4039(1997)38:27<4831:ACSO3A>2.0.ZU;2-I
Abstract
The tandem nucleophilic addition-aldol reaction of 3,4-pentadien-2-one , iodide ion, and aldehydes in the presence of ZrCl4 as the catalyst g ave the 3-iodohomoallylic alcohols in good yields, which could be furt her transformed to alpha,beta-unsaturated gamma-lactones by palladium- catalysed cyclocarbonylation. (C) 1997 Elsevier Science Ltd.