Positive response to immunomodulatory therapy in an adult patient with Rasmussen's encephalitis

Rasmussen's encephalitis (RE) is a rare and progressive neurologic conditio n of uncertain etiology that typically has a childhood onset. The authors d escribe a 45-year-old woman with adult-onset progressive aphasia, right hem iparesis, severe drug refractory epilepsy, and left cerebral hemisphere atr ophy. High-dose corticosteroids and plasmapheresis were not effective. She improved with high-dose therapy with human IV immunoglobulin.