Neurophysiological characterization of parkinsonian syndromes

Electrophysiological examination can provide relevant information on functi onal abnormalities in patients with parkinsonism. The combined use of vario us electrodiagnostic techniques can contribute to the diagnosis of the illn ess, to its correct classification and differentiation from other diseases with a clinically similar presentation, and in particular the identificatio n of the pathophysiological processes underlying some of the signs and symp toms characterizing the movement disorder. Tests which are useful in the di fferential diagnosis of various parkinsonian syndromes can now be performed in most electrodiagnostic laboratories. This article reviews same of the m ost relevant observations provided by neurophysiological studies on patient s with parkinsonism, with a special focus on those that could be of more va lue in neurological clinical practice through their contribution to the cha racterization of the disease or to the recognition of underlying pathophysi ological processes. (C) 2000 Editions scientifiques et medicates Elsevier S AS.