MetaFam is a comprehensive relational database of protein family informatio
n. This web-accessible resource integrates data from several primary sequen
ce and secondary protein family databases. By pooling together the informat
ion from these disparate sources, MetaFam is able to provide the most compl
ete protein family sets available. Users are able to explore the interrelat
ionships among these primary and secondary databases using a powerful graph
ical visualization tool, MetaFamView. Additionally, users can identify corr
esponding sequence entries among the sequence databases, obtain a quick sum
mary of corresponding families (and their sequence members) among the famil
y databases, and even attempt to classify their own unassigned sequences. H
ypertext links to the appropriate source databases are provided at every le
vel of navigation. Global family database statistics and information are al
so provided. Public access to the date is available at http://metafam.ahc.u
mn.edu/.