Traceless solid-phase synthesis of substituted benzimidazoles via a base-cleavable linker

Authors
Tumelty, D Cao, K Holmes, CP
Citation
D. Tumelty et al., Traceless solid-phase synthesis of substituted benzimidazoles via a base-cleavable linker, ORG LETT, 3(1), 2001, pp. 83-86
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
1
Year of publication
2001
Pages
83 - 86
Database
ISI
SICI code
1523-7060(20010111)3:1<83:TSSOSB>2.0.ZU;2-3
Abstract
[GRAPHICS] A solid phase route to substituted benzimidazoles has been developed using a modified base labile linker strategy to release the final products in a t raceless manner. This approach permits the synthesis of diverse compounds i n moderate yields and high purity.