Between January 1991 and January 1998, a total of 15 patients underwent dir
ect injection sclerotherapy for painful peripheral venous malformations. Du
plex ultrasonography or venography was used in all cases for the detection
and localization of tortuous venous structures. Direct injection with absol
ute ethyl alcohol was performed in 12 patients, and Sotradecol or sodium mo
rrhuate was used in 5 patients. Provocative lidocaine testing was used in 2
patients in whom major nerves were in proximity to the malformations. All
patients underwent follow-up in the clinic with duplex examination after ea
ch sclerotherapy.
Clinical symptoms of all patients improved during average follow-up of 2.5
years (range: 3 months to 6 years.) Duplex examination was useful in detect
ing the venous component including the size and course of veins, which were
often less well seen on magnetic resonance imaging. Duplex study was helpf
ul in follow-up after sclerotherapy in all patients. Direct injection scler
otherapy is an acceptable treatment modality for venous malformations. Comp
lications are manageable, and regular follow-up with Duplex is helpful.