Efficacy of ofloxacin and other otic preparations for otitis externa

Ofloxacin otic is as effective in curing otitis externa in children (<12 ye ars of age) as is the preparation combining polymyxin/neomycin plus hydroco rtisone and as ciprofloxacin otic. Furthermore ofloxacin otic, as it requir es less frequent dosing, is likely to encourage greater patient adherence a nd consequently to achieve a better cure rate than both of these treatment options. Because a number of cases of otitis externa are complicated by an undiagnosed tympanic membrane perforation, the lack of ototoxicity associat ed with ofloxacin otic makes it a particularly safe option for use in these patients.