Ka. Kiehl et al., Neural sources involved in auditory target detection and novelty processing: An event-related fMRI study, PSYCHOPHYSL, 38(1), 2001, pp. 133-142
We used event-related functional magnetic resonance imaging (erfMRI) techni
ques to examine the cerebral sites involved with target detection and novel
ty processing of auditory stimuli. Consistent with the results from a recen
t erfMRI study in the visual modality, target processing was associated wit
h activation bilaterally in the anterior superior temporal gyrus, inferior
and middle frontal gyrus, inferior and superior parietal lobules, anterior
and posterior cingulate, thalamus, caudate, and the amygdala/hippocampal co
mplex. Analyses of the novel stimuli revealed activation bilaterally in the
inferior frontal gyrus, insula, inferior parietal lobule, and in the infer
ior, middle, and superior temporal gyri. These data suggest that the scalp
recorded event-related potentials (e.g., N2 and P3) elicited during similar
tasks reflect an ensemble of neural generators located in spatially remote
cortical areas.