Synthesis of fused thiazolothienopyrimidines

Authors
Vas'kevich, RI Khripak, SM Staninets, VI Zborovskii, YL Chernega, AN
Citation
Ri. Vas'Kevich et al., Synthesis of fused thiazolothienopyrimidines, RUSS J ORG, 36(7), 2000, pp. 1061-1066
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
36
Issue
7
Year of publication
2000
Pages
1061 - 1066
Database
ISI
SICI code
1070-4280(200007)36:7<1061:SOFT>2.0.ZU;2-1
Abstract
Cyclization of 2-allylthio- and 2-(2-propynylthio)thieno[2,3-d]pyrimidin-4( 3H)-ones under the action of bromine, iodine, and concentrated sulfuric aci d yields thiazolo[3,2-a]thieno[2,3-d]pyrimidin-5-one thiazolo[3,2-a]thieno[ 2,3- e]pyrimidin-4-one derivatives, depending on the electrophile nature.