Efficacy of amphotericin B colloidal dispersion in the treatment of mediterranean visceral leishmaniasis in immunocompetent adult patients

Authors
Gaeta, GB Maisto, A Di Caprio, D Scalone, A Pasquale, G Felaco, FM Galante, D Gradoni, L
Citation
Gb. Gaeta et al., Efficacy of amphotericin B colloidal dispersion in the treatment of mediterranean visceral leishmaniasis in immunocompetent adult patients, SC J IN DIS, 32(6), 2000, pp. 675-677
Citations number
12
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
ISSN journal
00365548 → ACNP
Volume
32
Issue
6
Year of publication
2000
Pages
675 - 677
Database
ISI
SICI code
0036-5548(2000)32:6<675:EOABCD>2.0.ZU;2-W
Abstract
Twelve immunocompetent adults with Mediterranean visceral leishmaniasis (VL ) were treated with amphotericin B colloidal dispersion (ABCD; 2 mg/kg/d fo r 7 d). All patients showed rapid clinical response without significant adv erse events. Two weeks after therapy they were parasitologically cured and no relapses occurred during 6 months. ABCD is a valid alternative in the ma nagement of Mediterranean VL in adult patients.