Recent developments in LC-MS-MS for the identification and measurement of nanoscale amounts of proteins and peptides

Authors
Thomas, R
Citation
R. Thomas, Recent developments in LC-MS-MS for the identification and measurement of nanoscale amounts of proteins and peptides, SPECTROSCOP, 16(1), 2001, pp. 28
Citations number
11
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
SPECTROSCOPY
ISSN journal
08876703 → ACNP
Volume
16
Issue
1
Year of publication
2001
Database
ISI
SICI code
0887-6703(200101)16:1<28:RDILFT>2.0.ZU;2-S
Abstract
This article provides a current review of recent developments in LC-MS-MS t echnology for the analysis of biomolecules. In particular, the study focuse s on an innovative approach called variable-flow/nanoscale capillary LC/ele ctrospray MS for identifying and measuring complex mixtures of proteins and peptides at the low femtomole level.