Synthesis of fluorescence labeled sialyl Lewis(x) glycosphingolipids

Authors
Gege, C Oscarson, S Schmidt, RR
Citation
C. Gege et al., Synthesis of fluorescence labeled sialyl Lewis(x) glycosphingolipids, TETRAHEDR L, 42(3), 2001, pp. 377-380
Citations number
30
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
3
Year of publication
2001
Pages
377 - 380
Database
ISI
SICI code
0040-4039(20010115)42:3<377:SOFLSL>2.0.ZU;2-N
Abstract
The pyrene and nitrobenzoxadiazole (NBD) labeled derivatives of the natural sialyl Lewis(X) glycosphingolipid 1 were chemically synthesized as targets for investigating microdomain formation in membranes. The fluorescent anal ogs 2 and 3 were prepared by replacing the natural amide-linked fatty acid with a fluorescent analog. (C) 2001 Elsevier Science Ltd. All rights reserv ed.