2-Acetoxyacrylonitrile: use as electrophile equivalent to acetaldehyde in the asymmetric Michael reaction using chiral imines

Authors
Keller, L Camara, C Pinheiro, A Dumas, F d'Angelo, J
Citation
L. Keller et al., 2-Acetoxyacrylonitrile: use as electrophile equivalent to acetaldehyde in the asymmetric Michael reaction using chiral imines, TETRAHEDR L, 42(3), 2001, pp. 381-383
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
3
Year of publication
2001
Pages
381 - 383
Database
ISI
SICI code
0040-4039(20010115)42:3<381:2UAEET>2.0.ZU;2-D
Abstract
The asymmetric Michael addition reaction between a variety of chiral imines and 2-acetoxyacrylonitrile, an electrophile equivalent to acetaldehyde, wa s reported. The resulting adducts were obtained in fair yields and with de and ee greater than or equal to 95%. (C) 2001 Elsevier Science Ltd. All rig hts reserved.