The economic use of precious chiral diphosphine ligands-DuPHOS and its rhodium(I) COD and NBD complexes

Authors
Borner, A Heller, D
Citation
A. Borner et D. Heller, The economic use of precious chiral diphosphine ligands-DuPHOS and its rhodium(I) COD and NBD complexes, TETRAHEDR L, 42(2), 2001, pp. 223-225
Citations number
28
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
2
Year of publication
2001
Pages
223 - 225
Database
ISI
SICI code
0040-4039(20010108)42:2<223:TEUOPC>2.0.ZU;2-Y
Abstract
The use of cationic Rh(DuPHOS) precatalysts for asymmetric hydrogenation be aring NBD (norbornadiene) as counter ligand has significant advantages over the application of the related COD (cyclooctadiene) complexes. Liberation of the active catalysts by hydrogenation of COD requires much more time tha n complete asymmetric hydrogenation of a prochiral substrate proceeding in parallel. Due to this feature expensive DuPHOS ligands are wasted by more t han 50%. (C) 2000 Elsevier Science Ltd. All rights reserved.