Nickel-catalysed synthesis of 3-chloroanilines and chloro aminopyridines via cross-coupling reactions of aryl and heteroaryl dichlorides with amines

Authors
Desmarets, C Schneider, R Fort, Y
Citation
C. Desmarets et al., Nickel-catalysed synthesis of 3-chloroanilines and chloro aminopyridines via cross-coupling reactions of aryl and heteroaryl dichlorides with amines, TETRAHEDR L, 42(2), 2001, pp. 247-250
Citations number
35
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
2
Year of publication
2001
Pages
247 - 250
Database
ISI
SICI code
0040-4039(20010108)42:2<247:NSO3AC>2.0.ZU;2-Z
Abstract
Selective monoamination of aryl and heteroaryl dichlorides has been carried out using a catalyst combination of Ni(0) associated to 2,2'-bipyridine. T he synthesis of novel 3-chloroanilines and chloro aminopyridines in good to excellent yields is allowed using an excess of amine, 10 or 20 mol% cataly st and short reaction times. (C) 2000 Elsevier Science Ltd. All rights rese rved.