Human stuttering is a simple example of the repetition of sounds or symbols
, sometimes associated with single letters, and may be used to illustrate t
he amazing repetition of amino acids (symbolized by a letter, e.g. W) in pr
oteins. A survey of available databases with highly improbable strings of s
ingle amino acids is tabulated. This paper concludes with a challenge to th
e crystallographic community to probe the structural origins of the structu
re-function relationship in this neglected area. When nature stutters, we s
hould pay attention.