Purpose: To emphasize the differences between angiolymphoid hyperplasia wit
h eosinophilia (ALHE) and Kimura's disease (KD), two entities often confuse
d in the ophthalmic literature.
Methods: Case report of a subcutaneous mass in the periocular region of a 4
5-year old woman and a MEDLINE review of the ophthalmic and non-ophthalmic
literature on ALHE and KD.
Results: The clinical and histopathological findings of the present case we
re consistent with ALHE, but not with KD, A survey of the current ophthalmi
c literature indicates that these two designations are still often used syn
onymously, despite that non-ophthalmic papers now separate ALHE from KD,
Conclusion: The clinical and histopathological features of ALHE are most of
ten distinctly different from KD and these entities should be clearly separ
ated in the ophthalmic literature.