This paper examines the applicability of the diffusion model to drug use. A
variety of studies that employ the diffusion model to examine drug-related
behaviour, including the use of alcohol, tobacco and illicit drugs, are di
scussed. Studies include those that focus on "natural" or spontaneous diffu
sion and those in which diffusion of a drug or a drug-related intervention
is planned. Most studies examined support the application of the diffusion
model in the study of drug use. The model is particularly valuable when new
substances are introduced to a population or subgroup. The addition of eco
nomic and other forms of availability as a determinant of adoption would in
crease the power of the model. Recommended directions for research are outl
ined. The diffusion model has been used successfully in the study of drug u
se for several decades. More rigorous designs would strengthen this type of
research and provide direction for policymakers and those involved in publ
ic health and education.