Prostatic phyllodes tumor, a rare entity. Pathologic and immunohistochemical study of one case

We report the case of a prostatic phyllodes tumor in a 47-year-old man. It measured 6 cm and was composed of a glandular component with leaf-like arch itecture, lined with two cellular layers, and a moderatly cellular stromal component, with no atypia and no mitosis. Basal cells were marked with high -molecular-weight cytokeratin antibody (34 beta E12) and stromal cells were marked with anti-vimentin and for some of them with CD34 antibodies. Prost atic phyllodes tumor is a rare lesion with uncertain prognosis. Total surgi cal removal is necessary because malignant transoformation to high-grade sa rcoma has been reported In our case the development of the tumor at the pos terior side of the prostate, the lack of PSA immunoreactivity and the prese nce of mucinous glands, sometimes "endocervical-like" could suggest an orig in from embryonic mullerian remenants in the prostatic utricle rather than urogenital sinus.