Mechanisms of macrolide resistance in clinical pneumococcal isolates in France

Authors
Fitoussi, F Doit, C Geslin, P Brahimi, N Bingen, E
Citation
F. Fitoussi et al., Mechanisms of macrolide resistance in clinical pneumococcal isolates in France, ANTIM AG CH, 45(2), 2001, pp. 636-638
Citations number
25
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
2
Year of publication
2001
Pages
636 - 638
Database
ISI
SICI code
0066-4804(200102)45:2<636:MOMRIC>2.0.ZU;2-B
Abstract
The genetic basis of macrolide resistance was investigated in a collection of 48 genotypically unrelated clinical isolates of Streptococcus pneumoniae obtained between 1987 and 1997 in France. All strains were resistant to er ythromycin, clindamycin, and streptogramin B, exhibiting a macrolide-lineos amide-streptogramin B resistance phenotype, and harbored the erm(B) gene. N one of the strains carried the mef(A) or erm(A) subclass erm(TR) gene.