Molecular motions in chloramphenicol studied by Cl-35 nuclear quadrupole and H-1 nuclear magnetic resonance spectroscopy

Authors
Nogaj, B Wasicki, J Glaser, A Bilski, P
Citation
B. Nogaj et al., Molecular motions in chloramphenicol studied by Cl-35 nuclear quadrupole and H-1 nuclear magnetic resonance spectroscopy, APPL MAGN R, 19(2), 2000, pp. 227-235
Citations number
10
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
APPLIED MAGNETIC RESONANCE
ISSN journal
09379347 → ACNP
Volume
19
Issue
2
Year of publication
2000
Pages
227 - 235
Database
ISI
SICI code
0937-9347(2000)19:2<227:MMICSB>2.0.ZU;2-R
Abstract
The Cl-35 nuclear quadrupole resonance (NQR) frequency (v(Q)), nuclear quad rupole spin-lattice relaxation time (T-1Q), H-1 nuclear magnetic resonance second moment (M-2) and nuclear magnetic spin-lattice relaxation time (T-1) were measured for polycrystalline chloramphenicol (drug) as a function of temperature. Hindered rotation of the CHCl2 group and the phenyl ring was d etected, the relevant activation energies were determined. The rotations ar e discussed in detail.