Cytomegalovirus pneumonitis, activated prothrombin time prolongation and subacute thyroiditis after unrelated allogeneic bone marrow transplantation

Authors
Kawano, C Muroi, K Akioka, T Izumi, T Kodera, Y Ozawa, K
Citation
C. Kawano et al., Cytomegalovirus pneumonitis, activated prothrombin time prolongation and subacute thyroiditis after unrelated allogeneic bone marrow transplantation, BONE MAR TR, 26(12), 2000, pp. 1347-1349
Citations number
19
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
26
Issue
12
Year of publication
2000
Pages
1347 - 1349
Database
ISI
SICI code
0268-3369(200012)26:12<1347:CPAPTP>2.0.ZU;2-T
Abstract
A 22-year-old female with acute myeloid leukemia (AML) in complete remissio n received a conditioning regimen containing antithymocyte globulin for an unrelated bone marrow transplant (BMT). After BMT, the patient suffered fro m cytomegalovirus (CMV) pneumonitis with markedly high levels of CMV antige nemia, activated prothrombin time (APTT) prolongation, and subacute thyroid itis. Recovery of CD4(+) cells was delayed as long as 1 year after BMT, An association between these three episodes and viral infection due to the del ayed recovery of CD4(+) cells is suggested.