Gw. Bell et Pj. Kelly, A study of anxiety, and midazolam-induced amnesia in patients having lowerthird molar teeth extracted, BR J ORAL M, 38(6), 2000, pp. 596-602
We studied 60 patients to find out whether anxiety affects the dose of mida
zolam necessary for sedation, and whether operating time, dose of midazolam
, or technique have any influence on levels of amnesia and anxiety A pilot
study preceded the main study in which 20 patients were given local anaesth
esia only and 20 local anaesthesia and intravenous sedation. Patients in th
e main study group (n = 60) received both local anaesthesia and intravenous
sedation, The dose required for sedation was not linked to amnesia, pulse
rate, blood pressure, or preoperative anxiety Sedation did significantly re
duce postoperative anxiety scores, (P < 0.001) and amnesia was affected by
operating time; complete surgical amnesia seemed to last about 25 minutes.
(C) 2000 The British Association of Oral and Maxillofacial Surgeons.