Concepts of Combinatorial Chemistry and Combinatorial Technologies

A survey of basic concepts of combinatorial chemistry and combinatorial tec hnologies and a great impact of this new approach on the traditional chemis try is presented. The main fields of application of CC/CT are reviewed and the reasons why CC/CT is so strongly needed and demanded are given. Be;ides obvious utilization of CC/CT in drug discovery, agrochemical research and research and development of new materials and catalysts also gain from this approach. The paper describes the origins and development of the technique , formed on the basis of probabilistic justifications. The applicability of combinatorial technologies and main combinatorial tools are described toge ther with computer-assisted combinatorial chemistry, molecular design and b iological methods of CC/CT. A Ist of important Web resources relevant to th e topic is also presented.