The rhamnose pathway

Authors
Giraud, MF Naismith, JH
Citation
Mf. Giraud et Jh. Naismith, The rhamnose pathway, CURR OP STR, 10(6), 2000, pp. 687-696
Citations number
47
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN STRUCTURAL BIOLOGY
ISSN journal
0959440X → ACNP
Volume
10
Issue
6
Year of publication
2000
Pages
687 - 696
Database
ISI
SICI code
0959-440X(200012)10:6<687:TRP>2.0.ZU;2-H
Abstract
L-Rhamnose is a deoxy sugar found widely in bacteria and plants. Evidence c ontinues to emerge about its essential role in many pathogenic bacteria. Th e crystal structures of two of the four enzymes involved in its biosyntheti c pathway have been reported and the other two have been submitted for publ ication. This pathway does not exist in humans, making enzymes of this path way very attractive targets for therapeutic intervention.