A randomized trial of endoscopic balloon dilation and endoscopic sphincterotomy for removal of bile duct stones in patients with a prior Billroth II gastrectomy
Jjghm. Bergman et al., A randomized trial of endoscopic balloon dilation and endoscopic sphincterotomy for removal of bile duct stones in patients with a prior Billroth II gastrectomy, GASTROIN EN, 53(1), 2001, pp. 19-26
Background: A prior Billroth II gastrectomy renders endoscopic sphincteroto
my (EST) more difficult in patients with bile duct stones. Endoscopic ballo
on dilation (EBD) is a relatively easy procedure that potentially reduces t
he risk of bleeding and perforation.
Methods: Thirty-four patients with bile duct stones and a previous Billroth
II gastrectomy were randomized to EST or EBD. Complications were graded in
a blinded fashion. Results were compared with those for a group of 180 pat
ients with normal anatomy from a previously reported randomized trial of EB
D versus EST.
Results: All stones were removed in 1 endoscopic retrograde cholangiopancre
atography in 14 of 16 patients who underwent EBD versus 14 of 18 who had ES
T (p = 1.00). Mechanical lithotripsy was used in 3 EBD procedures versus 4
EST procedures (p = 1.00). Early complications occurred in 3 patients who h
ad EBD versus 7 who underwent EST (p = 0.27). Three patients had bleeding a
fter EST; 1 patient had mild pancreatitis after EBD. The median time requir
ed for stone removal was 30 minutes in both groups. Compared with patients
with a normal anatomy, patients with a previous Billroth II gastrectomy had
a significantly increased risk of bleeding after EST (17% vs. 2%, relative
risk = 7.25, p < 0.05).
Conclusions: A prior Billroth II gastrectomy renders EST more difficult and
increases the risk of a complication. EBD in these patients is easy to per
form and is not associated with an increased need for mechanical lithotrips
y or a longer procedure time. The risk of bleeding is virtually absent afte
r EBD and the risk of pancreatitis after EBD seems not significantly increa
sed in these patients.