Catastrophic antiphospholipid syndrome in cancer

Antiphospholipid syndrome is characterized by the presence of antiphospholi pid antibodies resulting in arterial and venous thromboembolism. Apart from primary cases, this syndrome is often associated with autoimmune diseases. Around 50 cases of catastrophic antiphospholipid antibody syndrome have be en reported as yet. Authors describe the first case of catastrophic antipho spholipid syndrome associated with gastric cancer. Apart from presenting th e clinical case, authors also discuss the possible pathomechanism of this a ssociated disorder including the role of immunological factors, as well as antiphospholipid antibodies.