Frequency of HLA-B alleles in a caucasoid population determined by a two-stage PCR-SSOP typing strategy

High resolution PCR-SSOP typing methods for HLA-B identification have been established and applied to a Northern Ireland population, using large enoug h numbers to give dependable allele frequencies. The six systems, which ope rate independently of each other, are intended for use as secondary typing systems following HLA-B identification with a medium resolution PCR-SSOP te chnique. (C) American Society for Histocompatibility and Immunogenetics, 20 00. Published by Elsevier Science Inc.