Cb. Cooper et al., SYNTHESIS AND IN-VITRO ANTIBACTERIAL ACTIVITIES OF NOVEL CONFORMATIONALLY RESTRICTED HYGROMYCIN-A ANALOGS, Bioorganic & medicinal chemistry letters, 7(13), 1997, pp. 1747-1752
The preparation of semisynthetic conformationally restricted hygromyci
n A analogues are described. Antibacterial results from these compound
s suggest active conformations for this class of agents. (C) 1997 Else
vier Science Ltd.