Cardiac and great vessel thrombosis in Behcet's disease

Behcet's disease (BD) is a chronic relapsing systemic vasculitis in which o rogenital ulceration is a prominent feature. The disease affects many syste ms and causes hypercoagulability. We present a 27-year-old male patient who exhibited widespread great vessel thrombosis including right atrial and ve ntricular thrombi in the setting of right-sided infectious endocarditis and orogenital aphthous ulcerations and erythema nodosum due to BD. We reviewe d the enigmatic prothrombotic state of BD, and discuss our prior experience s in this field.