CONSTRAINED BETA-ALANINE BASED GPIIB IIIA ANTAGONISTS/

Authors
KLEIN SI CZEKAJ M MOLINO BF CHU V
Citation
Si. Klein et al., CONSTRAINED BETA-ALANINE BASED GPIIB IIIA ANTAGONISTS/, Bioorganic & medicinal chemistry letters, 7(13), 1997, pp. 1773-1778
Citations number
34
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
13
Year of publication
1997
Pages
1773 - 1778
Database
ISI
SICI code
0960-894X(1997)7:13<1773:CBBGIA>2.0.ZU;2-L
Abstract
The concepts of centrally constrained and peptide based fibrinogen rec eptor antagonists have been successfully combined into a single series of analogs which have been demonstrated to be potent inhibitors of pl atelet aggregation. (C) 1997 Elsevier Science Ltd.