CATALYSIS OF PHOSPHODIESTER TRANSESTERIFICATION BY DINUCLEAR CU(II) COMPLEXES - THE ROLE OF THE 2ND CU(II) ION

Authors
LIU SH HAMILTON AD
Citation
Sh. Liu et Ad. Hamilton, CATALYSIS OF PHOSPHODIESTER TRANSESTERIFICATION BY DINUCLEAR CU(II) COMPLEXES - THE ROLE OF THE 2ND CU(II) ION, Bioorganic & medicinal chemistry letters, 7(13), 1997, pp. 1779-1784
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
13
Year of publication
1997
Pages
1779 - 1784
Database
ISI
SICI code
0960-894X(1997)7:13<1779:COPTBD>2.0.ZU;2-W
Abstract
Two novel dinuclear Cu(II) complexes are prepared and shown to be high ly active catalysts for phosphodiester transesterification. Comparativ e studies on the dinuclear complexes and corresponding mononuclear com plexes reveal that one dinuclear complex achieves high activity by dou ble Lewis acid and double general base catalysis while the other explo its single Lewis acid and double general base catalysis. (C) 1997 Else vier Science Ltd.