Tg. Voznesenskaya et al., Disorders of eating behavior and comorbid syndromes in obesity and methodsof their correction, IAN FIZ, 64(11), 2000, pp. 49-52
Eating behavior and comorbid syndromes were investigated in 40 women with o
besity. A frequent combination of obesity with disorders of eating behavior
, with emotional-personality, psychoautonomic and algesic disorders as well
as with appearance of affective disorders during dietetic nutrition (<<die
tetic depression>>) required their correction. As a result of insufficiency
of serotoninergic system of brain in pathogenesis of such disorders, fluox
etine (prozac)-a selective inhibitor of serotonine reuptake - was used for
treatment of eating disorders. Heterogeneity in the structure of the obesit
y is shown. Disorders of eating behavior were combined with pronounced anxi
ety, depression, algesic and psychoautonomic syndromes. Therapy with prozac
during 3 months in dose of 20 mg daily resulted in decrease of weight. Nor
malization of eating pattern, decrease of anxiety, depression, reaction to
the external stimuli, increase of stress-resistance of patients, alteration
s in eating liking, decrease of severity of disorders comorbid to obesity w
ere observed. A conclusion is made that prozac is indicated for patients in
whom pathology of eating behavior plays a significant role in pathogenesis
of obesity.