Polymers imprinted with chiral templates offer a new generation of tailor-m
ade chiral stationary phases (CSPs) with predictable selectivities. This re
view summarizes the present state of the art of molecular imprinting to gen
erate tailor-made CSPs and provides an overview of the main factors involve
d in the manufacturing process that are crucial to the chromatographic perf
ormance of the phases. (C) 2001 Elsevier Science B.V. All rights reserved.